ATAVON PRO Atovaquone & Proguanil HCl Chewable Tablets

Composition

Each uncoated chewable tablet contains:

• Atovaquone USP – 250 mg

• Proguanil Hydrochloride IP – 100 mg

Class

Anti-Protozoal

Indications / Uses

ATAVON-PRO is indicated for combination therapy in:

• Relapsing Babesiosis in dogs

• Resistant Babesia gibsoni infections

• Mixed tick-borne infections, including:

  • Babesia canis

  • Babesia gibsoni

  • Ehrlichia canis

  • Anaplasma platys

  • Hepatozoon canis

Dosage

• Atovaquone: 12.5 mg/kg body weight

• Proguanil: 5 mg/kg body weight

Administer once daily for 10 days, along with:

• Azithromycin: 10 mg/kg body weight

• Artesunate: 12.5 mg/kg body weight

Dosage and duration must be strictly followed as prescribed by the veterinarian.

Recommended Combination Protocols

• ATAVON-PRO + MACROZEE + ARTEBABE
  → For relapsing babesiosis

• ATAVON-PRO + MACROZEE + ARTEBABE + IMIDOPET
  → For severe tick fever with mixed haemoprotozoan infections

Pharmacodynamics

Atovaquone acts as a competitive inhibitor of ubiquinol, selectively blocking the mitochondrial electron transport chain at the bc1 complex. This inhibition leads to mitochondrial dysfunction and suppression of purine and pyrimidine biosynthesis, resulting in protozoal death.

Proguanil is a biguanide derivative that is metabolized into cycloguanil, its active form. It inhibits parasitic dihydrofolate reductase, disrupting DNA synthesis. Proguanil provides causal prophylactic, suppressive, and curative activity against protozoal infections.

Directions for Use

• Tablets may be given whole or split, as required

• Always administer with a fatty diet to improve Atovaquone absorption

• When used with Azithromycin:

  • Give Azithromycin on an empty stomach, preferably in the morning

• Complete the full treatment course to prevent relapse

Side Effects

• Atovaquone has a favourable safety profile with no commonly reported adverse effects

• Proguanil also has a high safety margin

Rare effects with prolonged use may include:

• Temporary hair loss

• Mouth ulcers

Precautions

• No specific contraindications reported for pregnant or young animals

• Use only under veterinary supervision

• Combination therapy is essential to prevent resistance and relapse

Storage

• Store in a cool, dry place

• Keep at room temperature

• Keep out of reach of children and pets

Shipping Policy
We offer free standard shipping on orders above ₹1999

• Within 5 km: 20–30 mins delivery

• 5–15 km: 1–2 hours

• 15–30 km: 2–4 hours

• Outside Hyderabad: 3–5 business days

Delivery timelines may vary due to traffic, weather, or other factors. Tracking details will be shared once the order is dispatched.

Returns & Cancellations
Returns are accepted within 2 days of delivery for unused, unopened products in original packaging with proof of purchase.

• Non-returnable items: Opened pet food, perishable products, clearance items, or custom orders.

• Damaged or wrong item? Contact us within 24–48 hours for a free replacement or refund.

• Refunds: Processed in 2–3 business days after we receive the product.

Orders can be canceled before dispatch only.

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